Host: |
Rabbit |
Applications: |
ELISA/IHC/IP/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-DNER (700-737) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Purification: |
Affinity Purified |
Concentration: |
0.5-1.5 µg/µl |
Dilution Range: |
WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200IHC: 1:50-1:200 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
DNER |
Gene ID: |
92737 |
Uniprot ID: |
DNER_HUMAN |
Immunogen Region: |
700-737 |
Immunogen: |
Synthetic peptide taken within amino acid region 700-737 on human Delta and Notch-like Epidermal growth factor-related receptorprotein. |
Tissue Specificity | Expressed in brain, spinal cord and adrenal gland. |
Function | Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. |
Protein Name | Delta And Notch-Like Epidermal Growth Factor-Related Receptor |
Database Links | Reactome: R-HSA-2122948 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPresent On The Membrane Of Dendrites And Cell Bodies But Excluded From Axonal MembraneAlso Found In Early Endosomes In The Somatodendritic Region |
Alternative Antibody Names | Anti-Delta And Notch-Like Epidermal Growth Factor-Related Receptor antibodyAnti-DNER antibodyAnti-BET antibodyAnti-UNQ262 antibodyAnti-PRO299 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance