Host: | Rabbit |
Applications: | ELISA/IP/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-DNER (700-737) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Biotin |
Isotype: | IgG |
Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
Purification: | Affinity Purified |
Concentration: | 0.5-1.5 µg/µl |
Dilution Range: | WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200IHC: 1:50-1:200 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | DNER |
Gene ID: | 92737 |
Uniprot ID: | DNER_HUMAN |
Immunogen Region: | 700-737 |
Immunogen: | Synthetic peptide taken within amino acid region 700-737 on human Delta and Notch-like Epidermal growth factor-related receptorprotein. |
Tissue Specificity | Expressed in brain, spinal cord and adrenal gland. |
Function | Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. |
Protein Name | Delta And Notch-Like Epidermal Growth Factor-Related Receptor |
Database Links | Reactome: R-HSA-2122948 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPresent On The Membrane Of Dendrites And Cell Bodies But Excluded From Axonal MembraneAlso Found In Early Endosomes In The Somatodendritic Region |
Alternative Antibody Names | Anti-Delta And Notch-Like Epidermal Growth Factor-Related Receptor antibodyAnti-DNER antibodyAnti-BET antibodyAnti-UNQ262 antibodyAnti-PRO299 antibody |
Information sourced from Uniprot.org