| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DnaJ homolog subfamily C member 3 (80-160 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNAJC3 |
| Gene ID: |
5611 |
| Uniprot ID: |
DNJC3_HUMAN |
| Immunogen Region: |
80-160 aa |
| Specificity: |
DNJC3 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 80-160 |
| Function | Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. |
| Protein Name | Dnaj Homolog Subfamily C Member 3Endoplasmic Reticulum Dna J Domain-Containing Protein 6Er-Resident Protein Erdj6Erdj6Interferon-Induced - Double-Stranded Rna-Activated Protein Kinase InhibitorProtein Kinase Inhibitor Of 58 KdaProtein Kinase Inhibitor P58 |
| Database Links | Reactome: R-HSA-192823Reactome: R-HSA-381038Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
| Cellular Localisation | Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 3 antibodyAnti-Endoplasmic Reticulum Dna J Domain-Containing Protein 6 antibodyAnti-Er-Resident Protein Erdj6 antibodyAnti-Erdj6 antibodyAnti-Interferon-Induced - Double-Stranded Rna-Activated Protein Kinase Inhibitor antibodyAnti-Protein Kinase Inhibitor Of 58 Kda antibodyAnti-Protein Kinase Inhibitor P58 antibodyAnti-DNAJC3 antibodyAnti-P58IPK antibodyAnti-PRKRI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
