Host: | Rabbit |
Applications: | WB/IF/ICC/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Monoclonal |
Clone ID : | S1MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DNAJC15 |
Gene ID: | 29103 |
Uniprot ID: | DJC15_HUMAN |
Immunogen Region: | 70-150 |
Specificity: | A synthetic peptide corresponding to a sequence within amino acids 70-150 of human DNAJC15 (Q9Y5T4). |
Immunogen Sequence: | ETAKKISTPSFSSYYKGGFE QKMSRREAGLILGVSPSAGK AKIRTAHRRVMILNHPDKGG SPYVAAKINEAKDLLETTTK H |
Tissue Specificity | Expressed at highest levels in heart, followed by liver and kidney. |
Function | Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP. Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9. |
Protein Name | Dnaj Homolog Subfamily C Member 15Cell Growth-Inhibiting Gene 22 ProteinMethylation-Controlled J ProteinMcj |
Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
Alternative Antibody Names | Anti-Dnaj Homolog Subfamily C Member 15 antibodyAnti-Cell Growth-Inhibiting Gene 22 Protein antibodyAnti-Methylation-Controlled J Protein antibodyAnti-Mcj antibodyAnti-DNAJC15 antibodyAnti-DNAJD1 antibodyAnti-GIG22 antibodyAnti-HSD18 antibody |
Information sourced from Uniprot.org