Anti-DNAH8 antibody (2086-2136 aa) (STJ197704)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DYH8 at the amino acid range 2086-2136
General Information
| Short Description | Rabbit polyclonal anti-Dynein axonemal heavy chain 8 (2086-2136 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNAH8 |
| Gene ID | 1769 |
| Uniprot ID | DYH8_HUMAN |
| Immunogen | Synthesized peptide derived from the human DYH8 at the amino acid range 2086-2136 |
| Immunogen Region | 2086-2136 aa |
| Specificity | This antibody detects endogenous levels of human DYH8 |
Additional Info
| Function | Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity.the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility.implicated in sperm flagellar assembly. |
| Protein Name | Dynein Axonemal Heavy Chain 8Axonemal Beta Dynein Heavy Chain 8Ciliary Dynein Heavy Chain 8 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum AxonemeDetected In Sperm TailWith Almost Exclusive Localization To The Principal PieceAlso Detected In The Cytoplasm Of Primary Spermatocytes |
| Alternative Antibody Names | Anti-Dynein Axonemal Heavy Chain 8 antibodyAnti-Axonemal Beta Dynein Heavy Chain 8 antibodyAnti-Ciliary Dynein Heavy Chain 8 antibodyAnti-DNAH8 antibody |
Information sourced from Uniprot.org