• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using DLX5 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HeLa, 293, and COLO205 cells, using DLX5 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Dlx-5 Polyclonal Antibody diluted at 1：500

Anti-DLX5 antibody (91-140 aa) (STJ92725)

SKU:
STJ92725

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Homeobox protein DLX-5 (91-140 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DLX5
Gene ID: 1749
Uniprot ID: DLX5_HUMAN
Immunogen Region: 91-140 aa
Specificity: Dlx-5 Polyclonal Antibody detects endogenous levels of Dlx-5 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human DLX5 at the amino acid range 91-140
Function Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.
Protein Name Homeobox Protein Dlx-5
Database Links Reactome: R-HSA-8939902
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Dlx-5 antibody
Anti-DLX5 antibody

Information sourced from Uniprot.org

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