| Tissue Specificity | Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta. |
| Post Translational Modifications | Ubiquitinated, leading to its degradation. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells. |
| Function | Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. |
| Protein Name | Disks Large-Associated Protein 5Dap-5Discs Large Homolog 7Disks Large-Associated Protein Dlg7Hepatoma Up-Regulated ProteinHurp |
| Database Links | Reactome: R-HSA-9013508 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindleLocalizes To The Spindle In Mitotic CellsColocalizes With Cdh1 At Sites Of Cell-Cell Contact In Intestinal Epithelial Cells |
| Alternative Antibody Names | Anti-Disks Large-Associated Protein 5 antibodyAnti-Dap-5 antibodyAnti-Discs Large Homolog 7 antibodyAnti-Disks Large-Associated Protein Dlg7 antibodyAnti-Hepatoma Up-Regulated Protein antibodyAnti-Hurp antibodyAnti-DLGAP5 antibodyAnti-DLG7 antibodyAnti-KIAA0008 antibody |
Information sourced from Uniprot.org
