| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-DLGAP1/GKAP (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.IHC: In paraffin embedded Human Cortex shows cytoplasm staining in neuronal cell bodies. Recommended concentration, 3-6µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | DLGAP1 |
| Gene ID: | 9229 |
| Uniprot ID: | DLGP1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_004737.2; NP_001003809.1 |
| Immunogen Sequence: | KISNEHSPKLQIRSH |
| Post Translational Modifications | Ubiquitinated by TRIM3.leading to proteasomal degradation. |
| Function | Part of the postsynaptic scaffold in neuronal cells. |
| Protein Name | Disks Large-Associated Protein 1Dap-1Guanylate Kinase-Associated ProteinHgkapPsd-95/Sap90-Binding Protein 1Sap90/Psd-95-Associated Protein 1Sapap1 |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinPostsynaptic DensitySynapse |
| Alternative Antibody Names | Anti-Disks Large-Associated Protein 1 antibodyAnti-Dap-1 antibodyAnti-Guanylate Kinase-Associated Protein antibodyAnti-Hgkap antibodyAnti-Psd-95/Sap90-Binding Protein 1 antibodyAnti-Sap90/Psd-95-Associated Protein 1 antibodyAnti-Sapap1 antibodyAnti-DLGAP1 antibodyAnti-DAP1 antibodyAnti-GKAP antibody |
Information sourced from Uniprot.org