Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Disks large homolog 2 (601-650 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DLG2 |
Gene ID: |
1740 |
Uniprot ID: |
DLG2_HUMAN |
Immunogen Region: |
601-650 aa |
Specificity: |
PSD-93 Polyclonal Antibody detects endogenous levels of PSD-93 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human DLG2 at the amino acid range 601-650 |
Function | Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses. |
Protein Name | Disks Large Homolog 2Channel-Associated Protein Of Synapse-110Chapsyn-110Postsynaptic Density Protein Psd-93 |
Database Links | Reactome: R-HSA-438066Reactome: R-HSA-442982Reactome: R-HSA-5673001Reactome: R-HSA-6794361Reactome: R-HSA-9609736Reactome: R-HSA-9617324Reactome: R-HSA-9620244 |
Cellular Localisation | Cell MembraneLipid-AnchorPostsynaptic DensitySynapseMembraneCell ProjectionAxonPerikaryonConcentrated In Soma And Postsynaptic Density Of A Subset Of Neurons |
Alternative Antibody Names | Anti-Disks Large Homolog 2 antibodyAnti-Channel-Associated Protein Of Synapse-110 antibodyAnti-Chapsyn-110 antibodyAnti-Postsynaptic Density Protein Psd-93 antibodyAnti-DLG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance