| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DLAT (1-290) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:20-1:50 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DLAT |
| Gene ID: |
1737 |
| Uniprot ID: |
ODP2_HUMAN |
| Immunogen Region: |
1-290 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DLAT (NP_001922.2). |
| Immunogen Sequence: |
MWRVCARRAQNVAPWAGLEA RWTALQEVPGTPRVTSRSGP APARRNSVTTGYGGVRALCG WTPSSGATPRNRLLLQLLGS PGRRYYSLPPHQKVPLPSLS PTMQAGTIARWEKKEGDKIN EGDLIAEVETDKATVGFESL EECYMAKILVAEGTRDVPIG AIICITVGKPEDIEAFKNYT LDSSAAPTPQAAPAPTPAAT ASPPTPSAQAPGSSYPPHMQ VLLPALSPTMTMGTVQRWE |
| Post Translational Modifications | Delipoylated at Lys-132 and Lys-259 by SIRT4, delipoylation decreases the PHD complex activity. |
| Function | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. |
| Protein Name | Dihydrolipoyllysine-Residue Acetyltransferase Component Of Pyruvate Dehydrogenase Complex - Mitochondrial70 Kda Mitochondrial Autoantigen Of Primary Biliary CirrhosisPbcDihydrolipoamide Acetyltransferase Component Of Pyruvate Dehydrogenase ComplexM2 Antigen Complex 70 Kda SubunitPyruvate Dehydrogenase Complex Component E2Pdc-E2Pdce2 |
| Database Links | Reactome: R-HSA-204174Reactome: R-HSA-389661Reactome: R-HSA-5362517Reactome: R-HSA-70268 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Dihydrolipoyllysine-Residue Acetyltransferase Component Of Pyruvate Dehydrogenase Complex - Mitochondrial antibodyAnti-70 Kda Mitochondrial Autoantigen Of Primary Biliary Cirrhosis antibodyAnti-Pbc antibodyAnti-Dihydrolipoamide Acetyltransferase Component Of Pyruvate Dehydrogenase Complex antibodyAnti-M2 Antigen Complex 70 Kda Subunit antibodyAnti-Pyruvate Dehydrogenase Complex Component E2 antibodyAnti-Pdc-E2 antibodyAnti-Pdce2 antibodyAnti-DLAT antibodyAnti-DLTA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
