Name: Anti-DKK1 nanobody [SAA1268] (STJN000062)
SKU: STJN000062
Availability: InStock

Anti-DKK1 nanobody [SAA1268] (STJN000062)

SKU:

STJN000062

£378.50 - £1,632.50

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Host:	Alpaca
Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Alpaca monoclonal nanobody anti-Dickkopf-Related Protein 1 is suitable for use in ELISA research applications.

Clonality :	Monoclonal
Clone ID :	SAA1268
Conjugation:	Unconjugated
Isotype:	VHH-8His-Cys-tag
Formulation:	0.01M PBS, pH 7.4.
Purification:	Purified by Nickel column.
Concentration:	1 mg/mL
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Function	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity.
Protein Name	Dickkopf-Related Protein 1 Dickkopf-1 Dkk-1 Hdkk-1 Sk
Database Links	Reactome: R-HSA-201681 Reactome: R-HSA-3772470 Reactome: R-HSA-5339717
Cellular Localisation	Secreted
Alternative Nanobody Names	Anti-Dickkopf-Related Protein 1 nanobody Anti-Dickkopf-1 nanobody Anti-Dkk-1 nanobody Anti-Hdkk-1 nanobody Anti-Sk nanobody Anti-DKK1 nanobody Anti-UNQ492 nanobody Anti-PRO1008 nanobody

Information sourced from Uniprot.org

Anti-DKK1 nanobody [SAA1268] (STJN000062)

General Information

Model	Name	Host	Clonality	Reactivity	Application
STJA0019022	Anti-DKK1 antibody [MOR04454] (STJA0019022)	Rat	Monoclonal	Human/Mouse	ELISA
STJA0021857	Anti-DKK1 antibody [SAA2072] (STJA0021857)	Mouse	Monoclonal	Human	ELISA/Neut
STJ98000	Anti-DKK1 antibody [2H2] (STJ98000)	Mouse	Monoclonal	Human	WB/ELISA
STJN000279	Anti-MLANA nanobody [SAA1259] (STJN000279)	Alpaca	Monoclonal	Human	ELISA
STJN000270	Anti-GRM2 nanobody [SAA1127] (STJN000270)	Alpaca	Monoclonal	Human	ELISA