• STJ72102 (0. 5µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-DIXDC1 antibody (Internal) (STJ72102)

SKU:
STJ72102-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-DIXDC1 (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.5-2µg/ml
ELISA-antibody detection limit dilution 1:64000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: DIXDC1
Gene ID: 85458
Uniprot ID: DIXC1_HUMAN
Immunogen Region: Internal
Accession Number: NP_001033043.1; NP_219493.1
Specificity: This antibody is expected to recognize both isoforms (NP_001033043.1; NP_219493.1).
Immunogen Sequence: DVSYHQVDLERE
Post Translational Modifications Phosphorylated on tyrosine and serine residues. Polyubiquitinated, leading to its proteasomal degradation. WNT3A signaling increases DIXDC1 protein levels by inhibiting its ubiquitination and subsequent degradation.
Function Positive effector of the Wnt signaling pathway.activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Protein Name Dixin
Coiled-Coil Protein Dix1
Coiled-Coil-Dix1
Dix Domain-Containing Protein 1
Cellular Localisation Cell Junction
Focal Adhesion
Cytoplasm
Cytoskeleton
Stress Fiber
Colocalizes With Gamma-Tubulin At The Centrosome
Both During Interphase And Mitosis
Associated With Actin Stress Fiber At The Filament Ends
Isoform 2: Cytoplasm
Not Associated With Stress Fibers
Alternative Antibody Names Anti-Dixin antibody
Anti-Coiled-Coil Protein Dix1 antibody
Anti-Coiled-Coil-Dix1 antibody
Anti-Dix Domain-Containing Protein 1 antibody
Anti-DIXDC1 antibody
Anti-CCD1 antibody
Anti-KIAA1735 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance