| Post Translational Modifications | Phosphorylated on tyrosine and serine residues. Polyubiquitinated, leading to its proteasomal degradation. WNT3A signaling increases DIXDC1 protein levels by inhibiting its ubiquitination and subsequent degradation. |
| Function | Positive effector of the Wnt signaling pathway.activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2. |
| Protein Name | DixinCoiled-Coil Protein Dix1Coiled-Coil-Dix1Dix Domain-Containing Protein 1 |
| Cellular Localisation | Cell JunctionFocal AdhesionCytoplasmCytoskeletonStress FiberColocalizes With Gamma-Tubulin At The CentrosomeBoth During Interphase And MitosisAssociated With Actin Stress Fiber At The Filament EndsIsoform 2: CytoplasmNot Associated With Stress Fibers |
| Alternative Antibody Names | Anti-Dixin antibodyAnti-Coiled-Coil Protein Dix1 antibodyAnti-Coiled-Coil-Dix1 antibodyAnti-Dix Domain-Containing Protein 1 antibodyAnti-DIXDC1 antibodyAnti-CCD1 antibodyAnti-KIAA1735 antibody |
Information sourced from Uniprot.org
