Anti-Dicarbonyl Reductase antibody (C-Term) (STJ70209)

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STJ70209-100
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Short Description :Goat polyclonal antibody anti-Dicarbonyl Reductase (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Applications:Pep-ELISA/WB/IHC
Host:Goat
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.5 mg/mL
Purification:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range:Peptide ELISA: antibody detection limit dilution 1:32000.
WB: Approx 26kDa band observed in human kidney, liver and testes lysates (calculated MW of 25.9kDa according to NP_057370.1). Recommended for use at 0.1-0.3µg/ml.
IHC: In paraffin embe
Formulation:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction:Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol:DCXR
Gene ID:51181
Uniprot ID:DCXR_HUMAN
Accession Number:NP_057370.1
Immunogen Region:C-Term
Immunogen Sequence:GSTLPVEGGFWAC
Function Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Protein Name L-Xylulose Reductase
Xr
Carbonyl Reductase Ii
Dicarbonyl/L-Xylulose Reductase
Kidney Dicarbonyl Reductase
Kidcr
Short Chain Dehydrogenase/Reductase Family 20c Member 1
Sperm Surface Protein P34h
Database Links Reactome: R-HSA-5661270
Reactome: R-HSA-5662853
Cellular Localisation Membrane
Peripheral Membrane Protein
Probably Recruited To Membranes Via An Interaction With Phosphatidylinositol
Alternative Antibody Names Anti-L-Xylulose Reductase antibody
Anti-Xr antibody
Anti-Carbonyl Reductase Ii antibody
Anti-Dicarbonyl/L-Xylulose Reductase antibody
Anti-Kidney Dicarbonyl Reductase antibody
Anti-Kidcr antibody
Anti-Short Chain Dehydrogenase/Reductase Family 20c Member 1 antibody
Anti-Sperm Surface Protein P34h antibody
Anti-DCXR antibody
Anti-SDR20C1 antibody

Information sourced from Uniprot.org