| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DHX30 |
| Gene ID: | 22907 |
| Uniprot ID: | DHX30_HUMAN |
| Immunogen Region: | 906-1155 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 906-1155 of human DHX30 (NP_055781.2). |
| Immunogen Sequence: | GWEEVLRWQDRSSRENYLEE NLLYAPSLRFIHGLIKQFSE NIYEAFLVGKPSDCTLASAQ CNEYSEEEELVKGVLMAGLY PNLIQVRQGKVTRQGKFKPN SVTYRTKSGNILLHKSTINR EATRLRSRWLTYFMAVKSNG SVFVRDSSQVHPLAVLLLTD GDVHIRDDGRRATISLSDSD LLRLEGDSRTVRLLKELRRA LGRMVERSLRSELAALPPSV QEEHGQLLALLAELLRGPC |
| Post Translational Modifications | Isoform 2: Phosphorylated on Ser-15. |
| Function | RNA-dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. |
| Protein Name | Atp-Dependent Rna Helicase Dhx30Deah Box Protein 30 |
| Cellular Localisation | CytoplasmMitochondrionMitochondrion MatrixMitochondrion NucleoidLocalizes To Mitochondrial Rna Granules Found In Close Proximity To The Mitochondrial NucleoidsRelocalizes To Stress Granules Upon Heat Stress |
| Alternative Antibody Names | Anti-Atp-Dependent Rna Helicase Dhx30 antibodyAnti-Deah Box Protein 30 antibodyAnti-DHX30 antibodyAnti-DDX30 antibodyAnti-KIAA0890 antibody |
Information sourced from Uniprot.org