Anti-DHRS7 antibody (STJ190742)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Dehydrogenase/reductase SDR family member 7 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DHRS7 |
| Gene ID | 51635 |
| Uniprot ID | DHRS7_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | DHRS7 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | NADPH-dependent oxidoreductase which catalyzes the reduction of a variety of compounds bearing carbonyl groups including steroids, retinoids and xenobiotics. Catalyzes the reduction/inactivation of 5alpha-dihydrotestosterone to 3alpha-androstanediol, with a possible role in the modulation of androgen receptor function. Involved in the reduction of all-trans-retinal to all-trans-retinol. Converts cortisone to 20beta-dihydrocortisone in vitro, although the physiological relevance of this activity is questionable. Reduces exogenous compounds such as quinones (1,2-naphtoquinone, 9,10-phenantrenequinone and benzoquinone) and other xenobiotics (alpha-diketones) in vitro, suggesting a role in the biotransformation of xenobiotics with carbonyl group. A dehydrogenase activity has not been detected so far. May play a role as tumor suppressor. |
| Protein Name | Dehydrogenase/Reductase Sdr Family Member 7Retinal Short-Chain Dehydrogenase/Reductase 4Retsdr4Short Chain Dehydrogenase/Reductase Family 34c Member 1Protein Sdr34c1 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneBound To The Endoplasmic Reticulum MembranePossibly Through A N-Terminus AnchorThe Main Bulk Of The Polypeptide Chain Was First Reported To Be Facing Toward The Lumen Of The Endoplasmic ReticulumHoweverIt Was Later Shown To Be Facing The Cytosol |
| Alternative Antibody Names | Anti-Dehydrogenase/Reductase Sdr Family Member 7 antibodyAnti-Retinal Short-Chain Dehydrogenase/Reductase 4 antibodyAnti-Retsdr4 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 34c Member 1 antibodyAnti-Protein Sdr34c1 antibodyAnti-DHRS7 antibodyAnti-DHRS7A antibodyAnti-RETSDR4 antibodyAnti-SDR34C1 antibodyAnti-CGI-86 antibodyAnti-UNQ285 antibodyAnti-PRO3448 antibody |
Information sourced from Uniprot.org