Anti-DHODH antibody (116-395) (STJ28979)

Name: Anti-DHODH antibody (116-395) (STJ28979)
SKU: STJ28979
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ28979

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Short Description	Rabbit polyclonal DHODH (116-395) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:100-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	DHODH
Gene ID	1723
Uniprot ID	PYRD_HUMAN
Immunogen Region	116-395
Immunogen Sequence	EIGSVTPKPQEGNPRPRVFR LPEDQAVINRYGFNSHGLSV VEHRLRARQQKQAKLTEDGL PLGVNLGKNKTSVDAAEDYA EGVRVLGPLADYLVVNVSSP NTAGLRSLQGKAELRRLLTK VLQERDGLRRVHRPAVLVKI APDLTSQDKEDIASVVKELG IDGLIVTNTTVSRPAGLQGA LRSETGGLSGKPLRDLSTQT IREMYALTQGRVPIIGVGGV SSGQDALEKIRAGASLVQL
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 116-395 of human DHODH (NP_001352.2).

Post Translational Modifications	The uncleaved transit peptide is required for mitochondrial targeting and proper membrane integration.
Function	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
Protein Name	Dihydroorotate Dehydrogenase Quinone - Mitochondrial Dhodehase Dihydroorotate Oxidase
Database Links	Reactome: R-HSA-500753
Cellular Localisation	Mitochondrion Inner Membrane Single-Pass Membrane Protein
Alternative Antibody Names	Anti-Dihydroorotate Dehydrogenase antibody Anti-Quinone - Mitochondrial antibody Anti-Dhodehase antibody Anti-Dihydroorotate Oxidase antibody Anti-DHODH antibody

Information sourced from Uniprot.org