| Host: | Rabbit |
| Applications: | IHC/IF/WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Diacylglycerol kinase kappa (1221-1270 aa) is suitable for use in Immunohistochemistry, Immunofluorescence, Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DGKK |
| Gene ID: | 139189 |
| Uniprot ID: | DGKK_HUMAN |
| Immunogen Region: | 1221-1270 aa |
| Specificity: | DGK-Kappa Polyclonal Antibody detects endogenous levels of DGK-Kappa protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DGKK at the amino acid range 1221-1270 |
| Post Translational Modifications | Phosphorylated at Tyr-78 by some member of the SRC family in response to H(2)O(2). |
| Function | Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). |
| Protein Name | Diacylglycerol Kinase KappaDag Kinase KappaDgk-Kappa142 Kda Diacylglycerol KinaseDiglyceride Kinase Kappa |
| Database Links | Reactome: R-HSA-114508 |
| Cellular Localisation | Cell MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Diacylglycerol Kinase Kappa antibodyAnti-Dag Kinase Kappa antibodyAnti-Dgk-Kappa antibodyAnti-142 Kda Diacylglycerol Kinase antibodyAnti-Diglyceride Kinase Kappa antibodyAnti-DGKK antibody |
Information sourced from Uniprot.org