Anti-DGKB antibody (657-706 aa) (STJ92697)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DGKB at the amino acid range 657-706
General Information
| Short Description | Rabbit polyclonal anti-Diacylglycerol kinase beta (657-706 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DGKB |
| Gene ID | 1607 |
| Uniprot ID | DGKB_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DGKB at the amino acid range 657-706 |
| Immunogen Region | 657-706 aa |
| Specificity | DGK-Beta Polyclonal Antibody detects endogenous levels of DGK-Beta protein. |
Additional Info
| Function | Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Has a higher activity with long-chain diacylglycerols like 1,2-di-(9Z-octadecenoyl)-sn-glycerol compared to 1,2-didecanoyl-sn-glycerol. Specifically expressed in brain, it regulates neuron-specific morphological changes including neurite branching and neurite spine formation. Isoform 2: Does not associate with membranes but has a diacylglycerol kinase activity. |
| Protein Name | Diacylglycerol Kinase BetaDag Kinase Beta90 Kda Diacylglycerol KinaseDiglyceride Kinase BetaDgk-Beta |
| Database Links | Reactome: R-HSA-114508 |
| Cellular Localisation | Postsynaptic Cell MembranePeripheral Membrane ProteinCell MembraneCytoplasmTranslocation To The Plasma Membrane Is Induced By Phorbol EstersIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Diacylglycerol Kinase Beta antibodyAnti-Dag Kinase Beta antibodyAnti-90 Kda Diacylglycerol Kinase antibodyAnti-Diglyceride Kinase Beta antibodyAnti-Dgk-Beta antibodyAnti-DGKB antibodyAnti-DAGK2 antibodyAnti-KIAA0718 antibody |
Information sourced from Uniprot.org