| Function | Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Has a higher activity with long-chain diacylglycerols like 1,2-di-(9Z-octadecenoyl)-sn-glycerol compared to 1,2-didecanoyl-sn-glycerol. Specifically expressed in brain, it regulates neuron-specific morphological changes including neurite branching and neurite spine formation. Isoform 2: Does not associate with membranes but has a diacylglycerol kinase activity. |
| Protein Name | Diacylglycerol Kinase BetaDag Kinase Beta90 Kda Diacylglycerol KinaseDiglyceride Kinase BetaDgk-Beta |
| Database Links | Reactome: R-HSA-114508 |
| Cellular Localisation | Postsynaptic Cell MembranePeripheral Membrane ProteinCell MembraneCytoplasmTranslocation To The Plasma Membrane Is Induced By Phorbol EstersIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Diacylglycerol Kinase Beta antibodyAnti-Dag Kinase Beta antibodyAnti-90 Kda Diacylglycerol Kinase antibodyAnti-Diglyceride Kinase Beta antibodyAnti-Dgk-Beta antibodyAnti-DGKB antibodyAnti-DAGK2 antibodyAnti-KIAA0718 antibody |
Information sourced from Uniprot.org
