Anti-Desmoplakin antibody (1672-1684) (STJ72283)

SKU:
STJ72283-100

Shipping:
Free Shipping
Current Stock:
Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Desmoplakin (1672-1684) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-Recommended concentration, 3-6µg/ml
ELISA-antibody detection limit dilution 1:4000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: DSP
Gene ID: 1832
Uniprot ID: DESP_HUMAN
Immunogen Region: 1672-1684
Accession Number: NP_004406.2
Specificity: This antibody is expected to recognize reported isoform I (NP_004406.2) only.
Immunogen Sequence: QESVKQAHLRNEH
Function Major high molecular weight protein of desmosomes. Regulates profibrotic gene expression in cardiomyocytes via activation of the MAPK14/p38 MAPK signaling cascade and increase in TGFB1 protein abundance.
Protein Name Desmoplakin
Dp
250/210 Kda Paraneoplastic Pemphigus Antigen
Database Links Reactome: R-HSA-351906
Reactome: R-HSA-6798695
Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Reactome: R-HSA-9696264
Reactome: R-HSA-9696273
Cellular Localisation Cell Junction
Desmosome
Cell Membrane
Localizes At The Intercalated Disk In Cardiomyocytes
Alternative Antibody Names Anti-Desmoplakin antibody
Anti-Dp antibody
Anti-250/210 Kda Paraneoplastic Pemphigus Antigen antibody
Anti-DSP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance