Anti-Desmoglein 1 antibody [R07-2K4] (STJA0035731)

SKU:
STJA0035731
€160.20 - €337.80
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Short Description :Rabbit monoclonal anti-Desmoglein 1 for use in WB, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/ICC/IF
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R07-2K4
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
IF 1:50-1:200
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:DSG1
Gene ID:1828
Uniprot ID:DSG1_HUMAN
Immunogen:A synthesized peptide derived from human DSG1
Tissue Specificity Expressed in all suprabasal layers of the epidermis, with the highest expression seen in the granular layer (at protein level).
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Protein Name Desmoglein-1
Cadherin Family Member 4
Desmosomal Glycoprotein 1
Dg1
Dgi
Pemphigus Foliaceus Antigen
Database Links Reactome: R-HSA-351906
Reactome: R-HSA-6798695
Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Reactome: R-HSA-9696264
Reactome: R-HSA-9696270
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Desmosome
Cytoplasm
Nucleus
Alternative Antibody Names Anti-Desmoglein-1 antibody
Anti-Cadherin Family Member 4 antibody
Anti-Desmosomal Glycoprotein 1 antibody
Anti-Dg1 antibody
Anti-Dgi antibody
Anti-Pemphigus Foliaceus Antigen antibody
Anti-DSG1 antibody
Anti-CDHF4 antibody

Information sourced from Uniprot.org