Anti-DENTT/CDA1 antibody (C-Term) (STJ70085)

SKU:
STJ70085-100
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Short Description :Goat polyclonal antibody anti-DENTT/CDA1 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications.
Applications:Pep-ELISA/IHC
Host:Goat
Reactivity:Human/Dog
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.5 mg/mL
Purification:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range:Peptide ELISA: antibody detection limit dilution 1:8000.
IHC: In paraffin embedded Human Testis shows nucleolar staining in spermatocytes. Recommended concentration, 5-10µg/ml.
Formulation:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction:Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol:TSPYL2
Gene ID:64061
Uniprot ID:TSYL2_HUMAN
Accession Number:NP_071400.1
Immunogen Region:C-Term
Immunogen Sequence:PNGWANPGKRGKTG
Post Translational Modifications Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
Function Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Protein Name Testis-Specific Y-Encoded-Like Protein 2
Tspy-Like Protein 2
Cell Division Autoantigen 1
Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4
Ctcl-Associated Antigen Se20-4
Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein
Nuclear Protein Of 79 Kda
Np79
Database Links Reactome: R-HSA-381038
Cellular Localisation Nucleus
Cytoplasm
Enriched In Transcriptionally Active Regions Of Chromatin In Neurons
Alternative Antibody Names Anti-Testis-Specific Y-Encoded-Like Protein 2 antibody
Anti-Tspy-Like Protein 2 antibody
Anti-Cell Division Autoantigen 1 antibody
Anti-Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4 antibody
Anti-Ctcl-Associated Antigen Se20-4 antibody
Anti-Differentially-Expressed Nucleolar Tgf-Beta1 Target Protein antibody
Anti-Nuclear Protein Of 79 Kda antibody
Anti-Np79 antibody
Anti-TSPYL2 antibody
Anti-CDA1 antibody
Anti-DENTT antibody
Anti-TSPX antibody
Anti-HRIHFB2216 antibody

Information sourced from Uniprot.org