| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
DENND5A |
| Gene ID: |
23258 |
| Uniprot ID: |
DEN5A_HUMAN |
| Immunogen Region: |
1150-1240 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1150-1240 of human DENND5A (NP_056028.2). |
| Immunogen Sequence: |
AFQHGFKSPRLFKNVFIWDF LEKAQTYYETLEKNEVVPEE NWHTRARNFCRFVTAINNTP RNIGKDGKFQMLVCLGARDH LLHHWIALLAD |
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth. |
| Protein Name | Denn Domain-Containing Protein 5aRab6-Interacting Protein 1Rab6ip1 |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | Golgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Denn Domain-Containing Protein 5a antibodyAnti-Rab6-Interacting Protein 1 antibodyAnti-Rab6ip1 antibodyAnti-DENND5A antibodyAnti-KIAA1091 antibodyAnti-RAB6IP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
