| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | DENND5A |
| Gene ID: | 23258 |
| Uniprot ID: | DEN5A_HUMAN |
| Immunogen Region: | 1150-1240 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1150-1240 of human DENND5A (NP_056028.2). |
| Immunogen Sequence: | AFQHGFKSPRLFKNVFIWDF LEKAQTYYETLEKNEVVPEE NWHTRARNFCRFVTAINNTP RNIGKDGKFQMLVCLGARDH LLHHWIALLAD |
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth. |
| Protein Name | Denn Domain-Containing Protein 5aRab6-Interacting Protein 1Rab6ip1 |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | Golgi Apparatus Membrane |
| Alternative Antibody Names | Anti-Denn Domain-Containing Protein 5a antibodyAnti-Rab6-Interacting Protein 1 antibodyAnti-Rab6ip1 antibodyAnti-DENND5A antibodyAnti-KIAA1091 antibodyAnti-RAB6IP1 antibody |
Information sourced from Uniprot.org