Anti-DENND1A antibody [SAA1871] (STJA0020299)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Denn Domain-Containing Protein 1a antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1871 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | DENND1A |
| Gene ID | 57706 |
| Uniprot ID | DEN1A_HUMAN |
Additional Info
| Function | Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes. Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P. |
| Protein Name | Denn Domain-Containing Protein 1aConnecdenn 1ConnecdennProtein Fam31a |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | Cytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinPresynaptic Cell MembraneAssociates To Membranes Via Lipid-Binding Activity |
| Alternative Antibody Names | Anti-Denn Domain-Containing Protein 1a antibodyAnti-Connecdenn 1 antibodyAnti-Connecdenn antibodyAnti-Protein Fam31a antibodyAnti-DENND1A antibodyAnti-FAM31A antibodyAnti-KIAA1608 antibody |
Information sourced from Uniprot.org