| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S8MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DEK |
| Gene ID: | 7913 |
| Uniprot ID: | DEK_HUMAN |
| Immunogen Region: | 51-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-200 of human DEK (P35659). |
| Immunogen Sequence: | SLIVEGKREKKKVERLTMQV SSLQREPFTIAQGKGQKLCE IERIHFFLSKKKTDELRNLH KLLYNRPGTVSSLKKNVGQF SGFPFEKGSVQYKKKEEMLK KFRNAMLKSICEVLDLERSG VNSELVKRILNFLMHPKPSG KPLPKSKKTC |
| Tissue Specificity | Ubiquitous. Expressed at relatively high levels. |
| Post Translational Modifications | Phosphorylated by CK2. Phosphorylation fluctuates during the cell cycle with a moderate peak during G(1) phase, and weakens the binding of DEK to DNA. |
| Function | Involved in chromatin organization. |
| Protein Name | Protein Dek |
| Database Links | Reactome: R-HSA-5250924Reactome: R-HSA-8864260Reactome: R-HSA-9616222 |
| Cellular Localisation | NucleusEnriched In Regions Where Chromatin Is Decondensed Or Sparse In The Interphase Nuclei |
| Alternative Antibody Names | Anti-Protein Dek antibodyAnti-DEK antibody |
Information sourced from Uniprot.org