| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Beta-Defensin (N-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS + 0.02% NaN3 |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:500-1:1000IHCICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DEFB1 |
| Gene ID: |
1672 |
| Uniprot ID: |
DEFB1_HUMAN |
| Immunogen Region: |
N-Term |
| Specificity: |
Reacts with the N-terminal region of human beta Defensin protein |
| Immunogen: |
Synthetic peptide corresponding to amino acids from the N-terminal region of human beta Defensin protein |
| Function | Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. |
| Protein Name | Beta-Defensin 1Bd-1Hbd-1Defensin - Beta 1 |
| Database Links | Reactome: R-HSA-1461957Reactome: R-HSA-1461973 |
| Cellular Localisation | SecretedMembraneAssociates With Tumor Cell Membrane-Derived Microvesicles |
| Alternative Antibody Names | Anti-Beta-Defensin 1 antibodyAnti-Bd-1 antibodyAnti-Hbd-1 antibodyAnti-Defensin - Beta 1 antibodyAnti-DEFB1 antibodyAnti-BD1 antibodyAnti-HBD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
