| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Beta-Defensin (N-Term) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS + 0.02% NaN3 |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DEFB1 |
| Gene ID: | 1672 |
| Uniprot ID: | DEFB1_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | Reacts with the N-terminal region of human beta Defensin protein |
| Immunogen: | Synthetic peptide corresponding to amino acids from the N-terminal region of human beta Defensin protein |
| Function | Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. |
| Protein Name | Beta-Defensin 1Bd-1Hbd-1Defensin - Beta 1 |
| Database Links | Reactome: R-HSA-1461957Reactome: R-HSA-1461973 |
| Cellular Localisation | SecretedMembraneAssociates With Tumor Cell Membrane-Derived Microvesicles |
| Alternative Antibody Names | Anti-Beta-Defensin 1 antibodyAnti-Bd-1 antibodyAnti-Hbd-1 antibodyAnti-Defensin - Beta 1 antibodyAnti-DEFB1 antibodyAnti-BD1 antibodyAnti-HBD1 antibody |
Information sourced from Uniprot.org