| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-DNA-binding death effector domain-containing protein 2 (226-276) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DEDD2 |
| Gene ID: | 162989 |
| Uniprot ID: | DEDD2_HUMAN |
| Immunogen Region: | 226-276 |
| Specificity: | This antibody detects endogenous levels of human DEDD2 |
| Immunogen: | Synthesized peptide derived from human DEDD2 AA range: 226-276 |
| Function | May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. |
| Protein Name | Dna-Binding Death Effector Domain-Containing Protein 2Ded-Containing Protein Flame-3Fadd-Like Anti-Apoptotic Molecule 3 |
| Cellular Localisation | NucleusNucleolusNuclearAccumulated In Subnuclear Structures Resembling Nucleoli |
| Alternative Antibody Names | Anti-Dna-Binding Death Effector Domain-Containing Protein 2 antibodyAnti-Ded-Containing Protein Flame-3 antibodyAnti-Fadd-Like Anti-Apoptotic Molecule 3 antibodyAnti-DEDD2 antibodyAnti-FLAME3 antibodyAnti-PSEC0004 antibody |
Information sourced from Uniprot.org
