| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DDX3Y (1-210) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DDX3Y |
| Gene ID: |
8653 |
| Uniprot ID: |
DDX3Y_HUMAN |
| Immunogen Region: |
1-210 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human DDX3Y (NP_001116137.1). |
| Immunogen Sequence: |
MSHVVVKNDPELDQQLANLD LNSEKQSGGASTASKGRYIP PHLRNREASKGFHDKDSSGW SCSKDKDAYSSFGSRDSRGK PGYFSERGSGSRGRFDDRGR SDYDGIGNRERPGFGRFERS GHSRWCDKSVEDDWSKPLPP SERLEQELFSGGNTGINFEK YDDIPVEATGSNCPPHIENF SDIDMGEIIMGNIELTRYTR PTPVQKHAIP |
| Tissue Specificity | Widely expressed at the mRNA level, with highest levels in testis. Testis-specific (at protein level). Expressed predominantly in spermatogonia, but occasionally detected in some pre-leptotene/leptotene spermatocytes. |
| Function | Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway. |
| Protein Name | Atp-Dependent Rna Helicase Ddx3yDead Box Protein 3 - Y-Chromosomal |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The Cytoplasm In An Xpo1-Dependent Manner |
| Alternative Antibody Names | Anti-Atp-Dependent Rna Helicase Ddx3y antibodyAnti-Dead Box Protein 3 - Y-Chromosomal antibodyAnti-DDX3Y antibodyAnti-DBY antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
