| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DDX3Y |
| Gene ID: | 8653 |
| Uniprot ID: | DDX3Y_HUMAN |
| Immunogen Region: | 1-210 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human DDX3Y (NP_001116137.1). |
| Immunogen Sequence: | MSHVVVKNDPELDQQLANLD LNSEKQSGGASTASKGRYIP PHLRNREASKGFHDKDSSGW SCSKDKDAYSSFGSRDSRGK PGYFSERGSGSRGRFDDRGR SDYDGIGNRERPGFGRFERS GHSRWCDKSVEDDWSKPLPP SERLEQELFSGGNTGINFEK YDDIPVEATGSNCPPHIENF SDIDMGEIIMGNIELTRYTR PTPVQKHAIP |
| Tissue Specificity | Widely expressed at the mRNA level, with highest levels in testis. Testis-specific (at protein level). Expressed predominantly in spermatogonia, but occasionally detected in some pre-leptotene/leptotene spermatocytes. |
| Function | Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway. |
| Protein Name | Atp-Dependent Rna Helicase Ddx3yDead Box Protein 3 - Y-Chromosomal |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The Cytoplasm In An Xpo1-Dependent Manner |
| Alternative Antibody Names | Anti-Atp-Dependent Rna Helicase Ddx3y antibodyAnti-Dead Box Protein 3 - Y-Chromosomal antibodyAnti-DDX3Y antibodyAnti-DBY antibody |
Information sourced from Uniprot.org