Anti-DDC antibody (1-137) (STJ23355)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DDC (1-137) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DDC |
| Gene ID | 1644 |
| Uniprot ID | DDC_HUMAN |
| Immunogen Region | 1-137 |
| Immunogen Sequence | MNASEFRRRGKEMVDYMANY MEGIEGRQVYPDVEPGYLRP LIPAAAPQEPDTFEDIINDV EKIIMPGVTHWHSPYFFAYF PTASSYPAMLADMLCGAIGC IGFSWAASPACTELETVMMD WLGKMLELPKAFLNEKA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human DDC (NP_000781.2). |
Additional Info
| Tissue Specificity | Isoform 2: High expression in kidney. |
| Function | Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin. |
| Protein Name | Aromatic-L-Amino-Acid DecarboxylaseAadcDopa DecarboxylaseDdc |
| Database Links | Reactome: R-HSA-209905Reactome: R-HSA-209931 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Aromatic-L-Amino-Acid Decarboxylase antibodyAnti-Aadc antibodyAnti-Dopa Decarboxylase antibodyAnti-Ddc antibodyAnti-DDC antibodyAnti-AADC antibody |
Information sourced from Uniprot.org