Anti-DCUN1D5 antibody (STJA0007796)

SKU:
STJA0007796
€60.00 - €315.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-DCN1-like protein 5 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DCUN1D5
Gene ID: 84259
Uniprot ID: DCNL5_HUMAN
Specificity: This antibody detects endogenous levels of DCUN1D5 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human DCUN1D5
Post Translational Modifications Phosphorylation at Ser-41 is independent of cullin's interaction. Phosphorylated in response to both TICAM1 and MYD88 dependent Toll-like receptor (TLR) pathway activation. Phosphorylated in response to IL1B stimulation.
Function Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth.
Protein Name Dcn1-Like Protein 5
Dcnl5
Dcun1 Domain-Containing Protein 5
Defective In Cullin Neddylation Protein 1-Like Protein 5
Squamous Cell Carcinoma-Related Oncogene 5
Database Links Reactome: R-HSA-8951664
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Spindle
Subcellular Localization Is Independent Of The Interaction With Cullins
Alternative Antibody Names Anti-Dcn1-Like Protein 5 antibody
Anti-Dcnl5 antibody
Anti-Dcun1 Domain-Containing Protein 5 antibody
Anti-Defective In Cullin Neddylation Protein 1-Like Protein 5 antibody
Anti-Squamous Cell Carcinoma-Related Oncogene 5 antibody
Anti-DCUN1D5 antibody
Anti-SCCRO5 antibody

Information sourced from Uniprot.org

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