| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Dynactin subunit 6 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DCTN6 |
| Gene ID: | 10671 |
| Uniprot ID: | DCTN6_HUMAN |
| Specificity: | This antibody detects endogenous levels of DCTN6 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human DCTN6 |
| Post Translational Modifications | Phosphorylation at Thr-186 by CDK1 during mitotic prometaphase creates a binding site for PLK1 that facilitates its recruitment to kinetochores. |
| Function | Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. |
| Protein Name | Dynactin Subunit 6Dynactin Subunit P27Protein Ws-3 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-3371497Reactome: R-HSA-6807878Reactome: R-HSA-6811436 |
| Cellular Localisation | CytoplasmCytoskeletonChromosomeCentromereKinetochore |
| Alternative Antibody Names | Anti-Dynactin Subunit 6 antibodyAnti-Dynactin Subunit P27 antibodyAnti-Protein Ws-3 antibodyAnti-DCTN6 antibodyAnti-WS3 antibody |
Information sourced from Uniprot.org
