| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dynactin subunit 6 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DCTN6 |
| Gene ID: |
10671 |
| Uniprot ID: |
DCTN6_HUMAN |
| Specificity: |
This antibody detects endogenous levels of DCTN6 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human DCTN6 |
| Post Translational Modifications | Phosphorylation at Thr-186 by CDK1 during mitotic prometaphase creates a binding site for PLK1 that facilitates its recruitment to kinetochores. |
| Function | Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. |
| Protein Name | Dynactin Subunit 6Dynactin Subunit P27Protein Ws-3 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-3371497Reactome: R-HSA-6807878Reactome: R-HSA-6811436 |
| Cellular Localisation | CytoplasmCytoskeletonChromosomeCentromereKinetochore |
| Alternative Antibody Names | Anti-Dynactin Subunit 6 antibodyAnti-Dynactin Subunit P27 antibodyAnti-Protein Ws-3 antibodyAnti-DCTN6 antibodyAnti-WS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
