Host: | Mouse |
Applications: | IHC/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-L-dopachrome tautomerase is suitable for use in Immunohistochemistry and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | 2A10 |
Conjugation: | Unconjugated |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IHC-P 1:50-200WB 1:1000-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DCT |
Gene ID: | 1638 |
Uniprot ID: | TYRP2_HUMAN |
Specificity: | This antibody detects endogenous levels of TRP2 DCT at Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from the human TRP2 DCT |
Function | Plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). |
Protein Name | L-Dopachrome TautomeraseDctDtL-Dopachrome Delta-IsomeraseTyrosinase-Related Protein 2Trp-2Trp2 |
Database Links | Reactome: R-HSA-5662702Reactome: R-HSA-9824585 |
Cellular Localisation | Melanosome MembraneSingle-Pass Type I Membrane ProteinMelanosomeProper Trafficking To Melanosome Is Regulated By Sgsm2Ankrd27Rab9aRab32 And Rab38 |
Alternative Antibody Names | Anti-L-Dopachrome Tautomerase antibodyAnti-Dct antibodyAnti-Dt antibodyAnti-L-Dopachrome Delta-Isomerase antibodyAnti-Tyrosinase-Related Protein 2 antibodyAnti-Trp-2 antibodyAnti-Trp2 antibodyAnti-DCT antibodyAnti-TYRP2 antibody |
Information sourced from Uniprot.org