• Western blot analysis of lysates from Jurkat cells, using DCP1A Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using SMIF Polyclonal Antibody

Anti-DCP1A antibody (111-160 aa) (STJ95708)

SKU:
STJ95708

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-mRNA-decapping enzyme 1A (111-160 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DCP1A
Gene ID: 55802
Uniprot ID: DCP1A_HUMAN
Immunogen Region: 111-160 aa
Specificity: SMIF Polyclonal Antibody detects endogenous levels of SMIF protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human DCP1A at the amino acid range 111-160
Function Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. Essential for embryonic development.
Protein Name Mrna-Decapping Enzyme 1a
Smad4-Interacting Transcriptional Co-Activator
Transcription Factor Smif
Database Links Reactome: R-HSA-430039
Reactome: R-HSA-450385
Reactome: R-HSA-450513
Reactome: R-HSA-975957
Cellular Localisation Cytoplasm
P-Body
Nucleus
Co-Localizes With Nanos3 In The Processing Bodies
Predominantly Cytoplasmic
In Processing Bodies (Pb)
Nuclear
After Tgfb1 Treatment
Translocation To The Nucleus Depends On Interaction With Smad4
Alternative Antibody Names Anti-Mrna-Decapping Enzyme 1a antibody
Anti-Smad4-Interacting Transcriptional Co-Activator antibody
Anti-Transcription Factor Smif antibody
Anti-DCP1A antibody
Anti-SMIF antibody

Information sourced from Uniprot.org

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