Anti-DC-SIGNR/CD299 antibody [SRM13269] (STJ11107999)

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STJ11107999
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Host: Rabbit
Applications: WB/IF/ICC/FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM13269
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB, 1:1000-1:5000
IF/ICC, 1:50-1:200
FC, 1:500-1:1000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CLEC4M
Gene ID: 10332
Uniprot ID: CLC4M_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Sequence: Human
Function Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for Ebolavirus. (Microbial infection) Acts as an attachment receptor for Hepatitis C virus. (Microbial infection) Acts as an attachment receptor for HIV-1. (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E. (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5. (Microbial infection) Acts as an attachment receptor for Influenzavirus. (Microbial infection) Acts as an attachment receptor for SARS-CoV. (Microbial infection) Acts as an attachment receptor for West-nile virus. (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus. (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein. (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule.
Protein Name C-Type Lectin Domain Family 4 Member M
Cd209 Antigen-Like Protein 1
Dc-Sign-Related Protein
Dc-Signr
Dendritic Cell-Specific Icam-3-Grabbing Non-Integrin 2
Dc-Sign2
Liver/Lymph Node-Specific Icam-3-Grabbing Non-Integrin
L-Sign
Cd Antigen Cd299
Database Links Reactome: R-HSA-9833110
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type Ii Membrane Protein
Isoform 2: Cell Membrane
Isoform 3: Cell Membrane
Isoform 5: Secreted
Isoform 6: Secreted
Isoform 7: Secreted
Isoform 10: Secreted
Alternative Antibody Names Anti-C-Type Lectin Domain Family 4 Member M antibody
Anti-Cd209 Antigen-Like Protein 1 antibody
Anti-Dc-Sign-Related Protein antibody
Anti-Dc-Signr antibody
Anti-Dendritic Cell-Specific Icam-3-Grabbing Non-Integrin 2 antibody
Anti-Dc-Sign2 antibody
Anti-Liver/Lymph Node-Specific Icam-3-Grabbing Non-Integrin antibody
Anti-L-Sign antibody
Anti-Cd Antigen Cd299 antibody
Anti-CLEC4M antibody
Anti-CD209L antibody
Anti-CD209L1 antibody
Anti-CD299 antibody

Information sourced from Uniprot.org

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