Host: | Goat |
Applications: | Pep-ELISA/WB-Trf |
Reactivity: | Human/Dog/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-DAPP1/BAM32 (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: In transfected HEK293 transiently expressing full-length Human DAPP1 (myc and DYKDDDDK tagged) , a band of approx. 35kDa was observed. No bands were observed in mock-transfected HEK293 |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | DAPP1 |
Gene ID: | 27071 |
Uniprot ID: | DAPP1_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_055210.2 |
Immunogen Sequence: | KLSQIRKQLNQGE |
Post Translational Modifications | Phosphorylated on tyrosine residues. |
Function | May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K. |
Protein Name | Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-PhosphoinositideHdapp1B Lymphocyte Adapter Protein Bam32B-Cell Adapter Molecule Of 32 Kda |
Database Links | Reactome: R-HSA-983695 |
Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinMembrane-Associated After Cell Stimulation Leading To Its Translocation |
Alternative Antibody Names | Anti-Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-Phosphoinositide antibodyAnti-Hdapp1 antibodyAnti-B Lymphocyte Adapter Protein Bam32 antibodyAnti-B-Cell Adapter Molecule Of 32 Kda antibodyAnti-DAPP1 antibodyAnti-BAM32 antibodyAnti-HSPC066 antibody |
Information sourced from Uniprot.org