Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-Cytokeratin 8&18 is suitable for use in Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | B22.1+B23.1 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
Dilution Range: | IHC 1: 100 – 1:500 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Background | Cytokeratins 8 &18 (CK 8 & 18) are expressed in most simple epithelia (e.g. thyroid, breast, gastrointestinal tract, and respiratory tract). Anti-CK 8 & 18 have been reported to stain most adenocarcinomas and squamous cell carcinomas, but not some well-differentiated squamous cell carcinomas. Cytokeratin 8 & 18 have been reported to be useful markers for identifying Paget cells, colorectal carcinoma metastases, 5 and gastric cancer micro metastases. |
Information sourced from Uniprot.org