![Anti-Cytokeratin 5 antibody [XM26] (STJ16101722)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152228/347080/STJ16101722_1__99829.1681999342.jpg?c=1 "Anti-Cytokeratin 5 antibody [XM26] (STJ16101722)")
![Anti-Cytokeratin 5 antibody [XM26] (STJ16101722)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152228/347080/STJ16101722_1__99829.1681999342.jpg?c=1 "Anti-Cytokeratin 5 antibody [XM26] (STJ16101722)")
Anti-Cytokeratin 5 antibody [XM26] (STJ16101722)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenProkaryotic recombinant fusion protein corresponding to a 103 amino acid portion of the C-terminal region of the human cytokeratin 5 molecule.
General Information
| Short Description | Mouse monoclonal anti-Cytokeratin 5 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | XM26 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | >=21 mg/L |
| Dilution Range | IHC-P 1:100 |
| Formulation | Tissue culture supernatant with Sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Prokaryotic recombinant fusion protein corresponding to a 103 amino acid portion of the C-terminal region of the human cytokeratin 5 molecule. |
Additional Info
| Background | Cytokeratins are a large family of cytoskeletal proteins found in epithelial cells. They are co-ordinately synthesized in pairs so that at least one member of each family is expressed in each epithelial cell. Cytokeratins assemble into obligatory heteropolymers composed of type I (acidic) and type II (basic) polypeptides to form higher order tetramers and protofilaments. Basal cells of human epidermis express acidic keratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58 kD protein that is closely related to cytokeratin 6. Point mutations in the cytokeratin 5 gene at locus 12q11-q13 can cause various types of epidermolysis bullosa simplex. Cytokeratin 5 is also reported to be expressed in most epithelial and biphasic mesotheliomas. Clone XM26 is specific for the 58 kD intermediate filament protein known as cytokeratin 5. It is not cross-reactive with cytokeratin 6. |
Information sourced from Uniprot.org