| Host: |
Rabbit |
| Applications: |
WB/IHC-P/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
SRM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:10000IHC-P:1:4000-1:20000ELISA:Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
KRT19 |
| Gene ID: |
3880 |
| Uniprot ID: |
K1C19_HUMAN |
| Immunogen Region: |
243-400 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 243-400 of human Cytokeratin 19 (KRT19) (NP_002267.2). |
| Immunogen Sequence: |
TDLAKILSDMRSQYEVMAEQ NRKDAEAWFTSRTEELNREV AGHTEQLQMSRSEVTDLRRT LQGLEIELQSQLSMKAALED TLAETEARFGAQLAHIQALI SGIEAQLGDVRADSERQNQE YQRLMDIKSRLEQEIATYRS LLEGQEDHYNNLSASKVL |
| Tissue Specificity | Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin. |
| Function | Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
| Protein Name | Keratin - Type I Cytoskeletal 19Cytokeratin-19Ck-19Keratin-19K19 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9725554 |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 19 antibodyAnti-Cytokeratin-19 antibodyAnti-Ck-19 antibodyAnti-Keratin-19 antibodyAnti-K19 antibodyAnti-KRT19 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
