Anti-Cytokeratin 14 antibody [EP1601Y+LL002] (STJ16101645)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit, Mouse
ConjugationUnconjugated
IsotypeIgG/IgG3
STJ16101645-7
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General Information

Short DescriptionRabbit, Mouse monoclonal anti-Cytokeratin 14 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostRabbit, Mouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDEP1601Y+LL002
IsotypeIgG/IgG3
ConjugationUnconjugated
FormulationTris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Storage InstructionStore at 2-8Β°C for up to 1-year, upon receipt.

Target Information

Additional Info

Background Cytokeratin 5 is an intermediate filament protein of 58 kD amongst the cytokeratin family. It is a type II (basic) cytokeratin. Antibodies to this protein identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.1Β Cytokeratin 14 is a 50 kD polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells.1Β Anti-cytokeratin 5 has been useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelial mesothelioma.2Β Anti-cytokeratin 14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors.3, 4 Anti-Cytokeratin 5, along with anti-cytokeratin 14, has been found to have an application in identifying the basal-likeΒ phenotype of breast carcinoma.5

Information sourced from Uniprot.org

Citations

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