Anti-Cytokeratin 12 antibody (250-494) [S5MR] (STJ11103015)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Cytokeratin 12 (KRT12) (250-494) antibody for use in WB, IHC-P, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT12 |
| Gene ID | 3859 |
| Uniprot ID | K1C12_HUMAN |
| Immunogen Region | 250-494 |
| Immunogen Sequence | EMQIESLNEELAYMKKNHED ELQSFRVGGPGEVSVEMDAA PGVDLTRLLNDMRAQYETIA EQNRKDAEAWFIEKSGELRK EISTNTEQLQSSKSEVTDLR RAFQNLEIELQSQLAMKKSL EDSLAEAEGDYCAQLSQVQQ LISNLEAQLLQVRADAERQN VDHQRLLNVKARLELEIETY RRLLDGEAQGDGLEESLFVT DSKSQAQSTDSSKDPTKTRK IKTVVQEMVNGEVVSSQVQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 250-494 of human Cytokeratin 12 (KRT12) (NP_000214.1). |
Additional Info
| Tissue Specificity | Expressed in the corneal epithelium (at protein level). |
| Function | Involved in corneal epithelium organization, integrity and corneal keratin expression. |
| Protein Name | Keratin - Type I Cytoskeletal 12Cytokeratin-12Ck-12Keratin-12K12 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 12 antibodyAnti-Cytokeratin-12 antibodyAnti-Ck-12 antibodyAnti-Keratin-12 antibodyAnti-K12 antibodyAnti-KRT12 antibody |
Information sourced from Uniprot.org