| Host: | Mouse |
| Applications: | IHC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Cytokeratin 1 for use in IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | SM0411 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Purification: | Affinity purification |
| Dilution Range: | IHC/IF (H) 1:500-1:1500 |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | KRT1 |
| Gene ID: | 3848 |
| Uniprot ID: | K2C1_HUMAN |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CK1 |
| Post Translational Modifications | Undergoes deimination of some arginine residues (citrullination). |
| Function | May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. |
| Protein Name | Keratin - Type Ii Cytoskeletal 167 Kda CytokeratinCytokeratin-1Ck-1Hair Alpha ProteinKeratin-1K1Type-Ii Keratin Kb1 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9725554 |
| Cellular Localisation | Cell MembraneCytoplasm |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 1 antibodyAnti-67 Kda Cytokeratin antibodyAnti-Cytokeratin-1 antibodyAnti-Ck-1 antibodyAnti-Hair Alpha Protein antibodyAnti-Keratin-1 antibodyAnti-K1 antibodyAnti-Type-Ii Keratin Kb1 antibodyAnti-KRT1 antibodyAnti-KRTA antibody |
Information sourced from Uniprot.org
![Anti-Multi-Cytokeratin antibody [AE-1/AE3] (STJ16101672)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/152178/347031/STJ16101672_1__28141.1681999285.jpg?c=1 "Anti-Multi-Cytokeratin antibody [AE-1/AE3] (STJ16101672)")
