| Host: | Mouse |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Cystatin C is suitable for use in ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 10005 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Purification: | Greater than 95% purity |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | 24 from manufacturing at 2–8°C. Temperature analysis:-70 °C, 21 days OK-20 °C, 21 days OK +4 °C, 21 days OK +35 °C, 7 days OK +35 °C, 21 days OK +45 °C, 3 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer. |
| Determination Method: | - |
| Immunoreactivity: | 80–120 % compared to the reference sample in an FIA test |
| Gene Symbol: | CST3 |
| Gene ID: | 1471 |
| Uniprot ID: | CYTC_HUMAN |
| Immunogen: | Human Cystatin C |
| Tissue Specificity | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland. |
| Post Translational Modifications | The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21. |
| Function | As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. |
| Protein Name | Cystatin-C Cystatin-3 Gamma-Trace Neuroendocrine Basic Polypeptide Post-Gamma-Globulin |
| Database Links | Reactome: R-HSA-381426 Reactome: R-HSA-6798695 Reactome: R-HSA-8957275 Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cystatin-C antibody Anti-Cystatin-3 antibody Anti-Gamma-Trace antibody Anti-Neuroendocrine Basic Polypeptide antibody Anti-Post-Gamma-Globulin antibody Anti-CST3 antibody |
Information sourced from Uniprot.org