Anti-CYP4Z1 antibody (71-120 aa) (STJ92604)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Cytochrome P450 4Z1 at the amino acid range 71-120
General Information
| Short Description | Rabbit polyclonal anti-Cytochrome P450 4Z1 (71-120 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CYP4Z1 |
| Gene ID | 199974 |
| Uniprot ID | CP4Z1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Cytochrome P450 4Z1 at the amino acid range 71-120 |
| Immunogen Region | 71-120 aa |
| Specificity | CYP4Z1 Polyclonal Antibody detects endogenous levels of CYP4Z1 protein. |
Additional Info
| Function | A cytochrome P450 monooxygenase that catalyzes the in-chain oxidation of fatty acids. Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates lauric and myristic acids predominantly at the omega-4 and omega-2 positions, respectively. Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Displays an absolute stereoselectivity in the epoxidation of arachidonic acid producing the 14(S),15(R)-epoxyeicosatrienoic acid (EET) enantiomer. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR.NADPH-ferrihemoprotein reductase). |
| Protein Name | Cytochrome P450 4z1Cypivz1Laurate 7-Monooxygenase |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinMicrosome Membrane |
| Alternative Antibody Names | Anti-Cytochrome P450 4z1 antibodyAnti-Cypivz1 antibodyAnti-Laurate 7-Monooxygenase antibodyAnti-CYP4Z1 antibodyAnti-UNQ3060 antibodyAnti-PRO9882 antibody |
Information sourced from Uniprot.org