• Western blot analysis of lysates from HeLa and Lovo cells, using Cytochrome P450 2U1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using CYP2U1 Polyclonal Antibody

Anti-CYP2U1 antibody (281-330 aa) (STJ92589)

SKU:
STJ92589

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cytochrome P450 2U1 (281-330 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CYP2U1
Gene ID: 113612
Uniprot ID: CP2U1_HUMAN
Immunogen Region: 281-330 aa
Specificity: CYP2U1 Polyclonal Antibody detects endogenous levels of CYP2U1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Cytochrome P450 2U1 at the amino acid range 281-330
Function A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR.NADPH-ferrihemoprotein reductase). Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. May down-regulate the biological activities of N-arachidonoyl-serotonin, an endocannabinoid that has anti-nociceptive effects through inhibition of fatty acid amide hydrolase FAAH, TRPV1 receptor and T-type calcium channels. Catalyzes C-2 oxidation of the indole ring of N-arachidonoyl-serotonin forming a less active product 2-oxo-N-arachidonoyl-serotonin.
Protein Name Cytochrome P450 2u1
Long-Chain Fatty Acid Omega-Monooxygenase
Database Links Reactome: R-HSA-211958
Reactome: R-HSA-2142816
Reactome: R-HSA-5579011
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Microsome Membrane
Mitochondrion Inner Membrane
Alternative Antibody Names Anti-Cytochrome P450 2u1 antibody
Anti-Long-Chain Fatty Acid Omega-Monooxygenase antibody
Anti-CYP2U1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance