Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Cytoplasmic FMR1-interacting protein 2 (1171-1220 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:10000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CYFIP2 |
Gene ID: |
26999 |
Uniprot ID: |
CYFP2_HUMAN |
Immunogen Region: |
1171-1220 aa |
Specificity: |
CYFIP2 Polyclonal Antibody detects endogenous levels of CYFIP2 |
Immunogen: |
Synthesized peptide derived from CYFIP2 at the amino acid range 1171-1220 |
Function | Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes. |
Protein Name | Cytoplasmic Fmr1-Interacting Protein 2P53-Inducible Protein 121 |
Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013149Reactome: R-HSA-9664422 |
Cellular Localisation | CytoplasmNucleusPerinuclear RegionSynapseSynaptosomeHighly Expressed In The Perinuclear Regionand Enriched In SynaptosomesTreatment With Leptomycin-B Triggers Translocation To The Nucleus |
Alternative Antibody Names | Anti-Cytoplasmic Fmr1-Interacting Protein 2 antibodyAnti-P53-Inducible Protein 121 antibodyAnti-CYFIP2 antibodyAnti-KIAA1168 antibodyAnti-PIR121 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance