| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Cytoplasmic FMR1-interacting protein 2 (1171-1220 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:10000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CYFIP2 |
| Gene ID: | 26999 |
| Uniprot ID: | CYFP2_HUMAN |
| Immunogen Region: | 1171-1220 aa |
| Specificity: | CYFIP2 Polyclonal Antibody detects endogenous levels of CYFIP2 |
| Immunogen: | Synthesized peptide derived from CYFIP2 at the amino acid range 1171-1220 |
| Function | Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes. |
| Protein Name | Cytoplasmic Fmr1-Interacting Protein 2P53-Inducible Protein 121 |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013149Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmNucleusPerinuclear RegionSynapseSynaptosomeHighly Expressed In The Perinuclear Regionand Enriched In SynaptosomesTreatment With Leptomycin-B Triggers Translocation To The Nucleus |
| Alternative Antibody Names | Anti-Cytoplasmic Fmr1-Interacting Protein 2 antibodyAnti-P53-Inducible Protein 121 antibodyAnti-CYFIP2 antibodyAnti-KIAA1168 antibodyAnti-PIR121 antibody |
Information sourced from Uniprot.org
