Anti-CYB5R4 antibody (380-460 aa) (STJ190373)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 380-460
General Information
| Short Description | Rabbit polyclonal anti-Cytochrome b5 reductase 4 (380-460 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CYB5R4 |
| Gene ID | 51167 |
| Uniprot ID | NB5R4_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 380-460 |
| Immunogen Region | 380-460 aa |
| Specificity | NB5R4 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin. |
| Protein Name | Cytochrome B5 Reductase 4Flavohemoprotein B5/B5rB5+B5rN-Terminal Cytochrome B5 And Cytochrome B5 Oxidoreductase Domain-Containing ProteinCb5/Cb5r |
| Database Links | Reactome: R-HSA-1237044 |
| Cellular Localisation | Endoplasmic ReticulumSoluble Protein |
| Alternative Antibody Names | Anti-Cytochrome B5 Reductase 4 antibodyAnti-Flavohemoprotein B5/B5r antibodyAnti-B5+B5r antibodyAnti-N-Terminal Cytochrome B5 And Cytochrome B5 Oxidoreductase Domain-Containing Protein antibodyAnti-Cb5/Cb5r antibodyAnti-CYB5R4 antibodyAnti-NCB5OR antibody |
Information sourced from Uniprot.org