| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Transmembrane ascorbate-dependent reductase CYB561 (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CYB561 |
| Gene ID: |
1534 |
| Uniprot ID: |
CY561_HUMAN |
| Immunogen Region: |
30-110 aa |
| Specificity: |
CY561 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 30-110 |
| Function | Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles. It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes. |
| Protein Name | Transmembrane Ascorbate-Dependent Reductase Cyb561Cytochrome B-561Cytochrome B561 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleChromaffin Granule MembraneMulti-Pass Membrane ProteinSecretory Vesicle Containing Catecholamines And Amidated Peptides |
| Alternative Antibody Names | Anti-Transmembrane Ascorbate-Dependent Reductase Cyb561 antibodyAnti-Cytochrome B-561 antibodyAnti-Cytochrome B561 antibodyAnti-CYB561 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
